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[DOI] [PubMed] [Google Scholar] 20.Zhang A., Jung E.C., Zhu H., Zou Y., Hui X., Maibach H
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In a 2019 study, Neelakantan and colleagues treated aged mice with a small-molecule NNMT inhibitor and reported activation of senescent muscle stem cells, enhanced proliferation and fusion, nearly two-fold greater muscle-fiber cross-sectional area after injury, a shift toward larger fibers, and roughly a 70% increase in peak torque relative to untreated aged mice
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