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Formation of nitrosothiol from the reaction between H 2 S and NO• or peroxynitrite (ONOO − ) was previously inferred and speculated to be important in blunting the effect of NO• (92)
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2.3 Metformin Metformin, a first-line oral therapy for type 2 diabetes, has garnered significant attention for its pleiotropic anti-cancer effects, making it a compelling candidate for drug repurposing in MPNs (85–87)
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