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As an example, curcumin has been found to be a non-toxic, low-affinity sarcoendoplasmic reticulum calcium ATPase (SERCA) pump inhibitor which allows F508del CFTR to escape from the endoplasmic reticulum and reach cell membrane (Egan et al., 2004
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However, upon evaluating allicin bioavailability from this garlic supplement in vivo through breath AMS production (Table 6), it was found to give high allicin bioavailability that was not significantly less than that of crushed raw garlic, regardless of meal type
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