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Indeed, inflammatory cells are sequestered in the pulmonary microvasculature and recruited into the airspaces following the generation of mediators such as IL-8, IL-1 and TNF-α in response to oxidative/nitrosative stress
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There are four families of PRRs distributed throughout all types of cells in the human body, namely, TOLL-like receptors (TLRs), NOD-like receptors (NLRs), retinoic acid-inducible gene I-like receptors RIG-I (RLRs), RIG-I receptors, and C-type lectin receptors (CLR)
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