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Centers for Medicare & Medicaid Services, “Medicare Advantage and Medicare Prescription Drug Programs to Remain Stable as CMS Implements Improvements to the Programs in 2025,” September 27, 2024, For a discussion of historical use of demonstration authority, see Meredith Freed et al., Moving the Needle on Prescription Drug Costs: Using the Innovation Center and Other Demonstration Authority , KFF, March 25, 2021, For more information on the GLP-1 Bridge demonstration, see Centers for Medicare & Medicaid Services, “Medicare GLP-1 Bridge,” July 13, 2026, Nicholas Bagley et al., “Most-Favored-Nation Drug Pricing—How Courts Could Shape Future Health Regulation,” JAMA Health Forum 6, no

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In this reaction, a single molecule of glucose-6-phosphate (in the presence of a water molecule and NADP+) produces two (2) molecules of NADPH and a single molecule of ribulose 5-phosphate