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Laboratory studies explore optimal administration regimens for different research objectives, including acute versus chronic senescent cell elimination and the effects of repeated administrations on tissue function and aging markers
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Lipid-mediated conformational changes in α-syn may involve interactions with cellular membranes: Binding to cholesterol-rich lipid rafts accelerates the transition of soluble α-syn monomers into insoluble fibrils, providing a molecular basis for LB formation (149,150)
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