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In parallel, translational studies must determine whether exerkine-targeted therapies or exercise mimetics can safely and reproducibly recapitulate the retinal benefits of physical activity, while accounting for inter-individual variability driven by age, disease stage, and metabolic status that may influence exerkine responsiveness and therapeutic feasibility
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Autopicked particle stacks were exported to cryoSPARC 52 for GluK3-SYM and cryoSPARC v2 for GluK3-UBP310 to carry out 2D classification
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