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Injection-site redness, swelling, or discomfort Infection risk from nonsterile injection practices Allergic reactions ranging from mild to severe Headaches or dizziness in some users Unknown long-term effects due to limited research Because adverse effect reports come from limited evidence, they do not confirm overall safety

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The symptoms recorded throughout history include convulsions, sores, hallucinations or mania, headaches, nausea, gangrene, and burning extremities.[ref] Modern grain processing methods eliminate ergot as a problem in human food sources, but it can still affect animals that graze on grasses or contaminated grains.[ref] The neuroactive components in the ergot alkaloids are similar to precursor molecules for LSD