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The identified prognostic signature provides a robust tool for predicting patient outcomes and may inform the development of targeted therapies aimed at modulating GSH metabolism and enhancing antitumor immunity in LUAD, thereby facilitating improved treatment decision-making and identification of high-risk populations requiring close follow-up
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The interaction of choroid plexus rhythmicity and behavior, especially in conditions affecting estrogen availability (e.g., menopause, hormone replacement therapy, estrogen-blocking cancer treatments like tamoxifen) remains an open question for future studies
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