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Individual sugar components utilized to generate glycans happen to be absorbed entirely via the cell or produced through multiple metabolic processes and include, but are not constrained to, glucose (Glu), mannose (Man), fucose (Fuc), N-acetylglucosamine (GlcNAc), and N-acetylgalactosamine (GalNAc)
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The same chemistry that drives tumour cell killing can oxidise lipids in ferroptosis-sensitive normal tissues such as the kidney and liver, so exposure and tissue selectivity must be tightly controlled
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