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However, when NEM (10 mg/kg), an inhibitor of the sulfhydryl groups, was administered, there was an exacerbation of ULA (299.7 ± 11.5 mm 2 ) with a reduction in the gastroprotective effect of carbenoxolone (100 mg/kg) and (-)-Carveol (100 mg/kg) for 49% (152.5 ± 25.1 mm 2 ) and 15% (254.7 ± 18.2 mm 2 ), respectively, compared to the groups in which the blocker was not administered (Figure 5A)

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Extrinsic Fas-mediated eryptosis A crucial step in the apoptosis mechanism in eukaryotic cells is the activation of caspases, a family of highly conserved cysteine proteases