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A decrease in the expression of mitochondrial chaperones such as HSP60 and HSP70, critical for protein folding and mtDNA replication, has also been observed [61]
laboratory reagent
Size:Size 7 - (37lbs+)
Inhibition of these enzymes by D-2HG results in genome-wide epigenetic alterations [68,76], including high H3K9 trimethylation and CpG island methylation [80,81,82]
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