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Indeed, a low concentration of 200 mg/day orally is capable of reducing IL-6 levels, which are inversely correlated with NKA release [73]
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In the context of ACT or spontaneous anti-tumor response, methionine restriction (MR) has been shown to induce immune checkpoint receptor expression and T cell exhaustion, resulting in impaired anti-tumor T cell responses (69, 70, 74)
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