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These results demonstrate that the modulation of the Wnt/β-catenin pathway can induce apoptotic cell death and autophagy through different mechanisms, and that the modulation (either activation or inhibition) of the Wnt/β-catenin pathway in multiple glioblastoma can induce apoptotic cell death and autophagy through the regulation of AMPK, c-myc, Hippo, and the p53 signaling pathway
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