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However, signaling through the IL-12Rβ2:gp130 heterodimeric receptor can also induce the production of iTr35 cells, which fully exert their immunosuppressive functions (Fig
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By simultaneously activating the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, it effectively promotes insulin secretion and reduces glucagon release, leading to better blood sugar regulation and weight loss support
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