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[DOI] [PubMed] [Google Scholar] 67.Baz MA, Tapson VF, Roggli VL, Van Trigt P, Piantadosi CA
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P450s can catalyze the conversion of hydrophobic intermediates of primary and secondary metabolic pathways through hydroxylation, dehalogenation, dealkylation, and nitro reduction and therefore neutralize the highly reactive nucleophile sites of the chemical and/or increasing its water-solubility facilitating its excretion from the cell (Pochapsky et al., 2018)
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