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In the correct orientation, the complete TCRฮฑฮฒ is expressed on the cell surface of thymocytes owing to the presence of a conventional transgene in these mice coding for the corresponding HY-TCRฮฒ chain 37
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In the cardiovascular system, new blood vessel formation from preexisting vasculature, in a process known as angiogenesis, is driven by vascular endothelial growth factor (VEGF) binding to VEGF receptor 2 (VEGFR-2) which promotes blood vessel development
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