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As part of a larger multi-protein complex, Prdx1 binding to the JNK-GSTP heterodimer occurs through GSTP and is mediated, at least in part, by Prdx1 catalytic Cys52, independently from the redox status of this protein [79]
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The most common side effects, nausea, constipation, and fatigue, are most prominent during this transition
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