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Mitochondrial Genetic Diseases and Ophthalmic Manifestations: Molecular Pathophysiology, Genetics, and Clinical Management
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Elevated levels of SN-38 in the blood lead to bone marrow toxicities characterized by leukopenia and neutropenia, as well as damage to the intestinal epithelial cells ( see Figure 6–6 ), resulting in acute and life-threatening diarrhea
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