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Increased energy expenditure through enhanced NAD+ salvage pathway By inhibiting NNMT, 5-Amino-1MQ prevents the methylation and clearance of nicotinamide, channeling it back into the NAD+ salvage pathway and boosting cellular energy metabolism
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All MS 4 experiments were performed on an LTQ linear ion trap mass spectrometer (Thermo Fisher Scientific, San Jose, CA, USA)
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