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In simple terms, our primary goals were to understand (1) what makes some cysteines more susceptible to oxidation than others, (2) trends and recurring motifs observed for the hydrogen bonding interactions of oxidized cysteines with other amino acids, and (3) the structural and dynamical consequences of cysteine oxidation in proteins, i.e., how these site-specific perturbations to the chemical structure modify the energy landscape, in ways that can ultimately impact function

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Size:500mg

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