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(ii) thioproline forms spontaneously in vivo from the condensation of HCHO and free or protein-bound cysteine [10,11]
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Functional experiments within colorectal and gastric cancer cell lines demonstrated that increased GPX4 levels boosted cellular proliferation, suggesting an oncogenic role for GPX4, a finding that aligns with previous researches ( Subsequently, we investigated the correlation between GPX4 expression and survival outcomes across a range of cancer types
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