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In one randomized controlled trial that included 137 healthy adults over 65 years of age, changes in cognitive function were no different in those assigned to the Mediterranean diet intervention than those assigned to eat their habitual diet after six months, suggesting possible benefits from a Mediterranean diet in healthy individuals may require more time to be detectable
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Phenotype of the Mat1a KO mouse links a reduction in the transmethylation capacity of the liver with hepatic steatosis and liver injury (144, 154)
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