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Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 4), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification
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Moreover, mice models of PD were treated with 20 µg of NAD + injection once, before injection with 6-hydroxydopamine to induce PD
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