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The disease was named “fatal granulomatous disease of childhood,” later changed to its current name, “chronic granulomatous disease” (CGD) ( Molecular genetics of chronic granulomatous disease Pathogenic variants in genes encoding subunits or regulatory proteins of the phagosomal NADPH oxidase complex cause CGD

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The gut carries PepT1, a transporter that pulls tripeptides into intestinal cells, and inflamed tissue appears to carry more of it