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Lysates were incubated with antibodies [NRF2 (proteintech, 80593-1-RR Clone No.1I21), KEAP1 (proteintech, 10503-2-AP) or IgG control (CST, #2729)] and Dynabeads ProteinG (ThermoFisher) with gentle rotation at 4 °C for 2 h
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