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Although direct evidence in PACs remains limited, this concept is biologically consistent with current mechanistic models of HTG-AP, in which excessive fatty acid flux and oxidative injury are central determinants of disease severity (60, 61)
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When GHK-Cu May Be More Relevant There are clinical scenarios where GHK-Cu may be considered as part of a broader strategy: Chronic degenerative tendon patterns Delayed remodeling after prolonged injury Skin and soft tissue repair needs Adjunctive support in structured combination protocols In frameworks such as the GLOW approach, sequencing is central
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