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However, even dual inhibition of RAF/EGFR in CRC can be overcome by wild-type NRAS amplification, which has been identified as a unique adaptive mechanism in CRC, but not in melanoma (78)
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[DOI] [PubMed] [Google Scholar] 55.Du M., Chang C., Zhang X., Zhang Y., Radford M.J., Gahler R.J., Kuo Y.C., Wood S., Solnier J
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