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Consistent with these ideas, redox proteomic studies reported increased HNE modification of BiP/Grp78 during AD pathology (342), which may cause the failure to bind to misfolded proteins, thereby contributing to the dysfunction of the UPR
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Five microliters of diluted sperm sample was placed on a glass slide along with 5 μL of reagent solution, allowed to sit for 30 s, and then evaluated under a microscope
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