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2 Institute of Clinical Oncology, The Second People’s Hospital of Lianyungang (Cancer Hospital of Lianyungang), Lianyungang, People’s Republic of China *These authors contributed equally to this work Correspondence: Xuzhu Gao, Institute of Clinical Oncology, The Second People’s Hospital of Lianyungang (Cancer Hospital of Lianyungang), Lianyungang, People’s Republic of China, Email [email protected] Abstract: The interleukin-6 (IL-6) family of cytokines includes IL-6, IL-11, IL-27, IL-31, etc