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As will be highlighted in the following, this can play a role in the proposed explanation of the important biological role of metallated MTs in several organs where the accumulation of metals over lifetime ultimately generates its functional failure or the onset of cancer
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mtROS-mediated Akt/AMPK/mTOR pathway was involved in Copper-induced autophagy and it attenuates Copper-induced apoptosis in RAW264.7 mouse monocytes
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