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For example, the MeSA esterase SABP2 from tobacco and its Arabidopsis ortholog MES9 have high affinities for SA (apparent K d = 0.092 and ~0.200 μM, respectively) (31, 32, 35), which are similar to those of NPR1 ( K d = 0.140–0.190 μM) (34) and NPR4 ( K d = 0.046 μM) ( K d = 1 μM) and approaches those of catalase ( K d = 15.5 μM) (36) and carbonic anhydrase ( K d = 3.7 μM) (37, 38)