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Freezing can cause freeze-concentration, where ice formation pushes the acid and peptide into shrinking pockets of liquid, concentrating the acid and damaging the peptide structure during the freeze-thaw process
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COMPARING THE ADVANTAGES OF EXOSOME AND STEM CELL THERAPIES Clinical trials have elucidated issues with the safety and stability of BMSCs that affect clinical treatment progression, clinical staging, and determining infusion volumes upon using BMSCs for the treatment of chronic liver disease, including HF and cirrhosis [83]
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