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l carnitine and uric acid Hyperuricemia its related diseases: mechanisms and advances in therapy One molecule shows up
One molecule shows up depleted in almost every major brain disorder. A 2022 review in Molecules maps glutathione's role in the brain — remarkable how many jobs this tripeptide handles: antioxidant defense
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Increased expression of NLRP3 and caspase-1 genes in peripheral blood mononuclear cells (PBMC) and elevated protein levels of NLRP3, caspase-1, and IL-1B in the blood plasma were found to correlate with PD severity (40), further supporting the perception of PD as a chronic systemic inflammatory disease
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