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The key enzyme in this activation pathway is arsenic methyltransferase (AS3MT), which catalyzes the methylation of inorganic arsenic to form metabolites such as monomethylarsonous acid (MMA III ) and Dimethylarsinous acid (DMA III )
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Histone lactylation promotes the expression of YTHDF2, which specifically recognizes the m6A modification sites on oncogene Per1 and TP53 RNA and promotes Per1 and TP53 mRNA degradation, thereby accelerating the development of ocular melanoma 80
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