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10.3390/foods11070974 55 JiH.ZhaoX.ChenX.FangH.GaoH.WeiG.et al (2024)
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This provides a potential mechanism whereby NPY/AgRP neurons can maintain a high ghrelin-induced firing rate during low energy states, whereas the anorexigenic pro-opiomelanocortin (POMC) neurons with their lack of GHSR receptor-induced UCP2 activation cannot buffer against ROS, as well, and thus, cannot maintain neuronal firing during starvation [45]
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