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Targeting epigenetic regulators as a promising avenue to overcome cancer therapy resistance | Signal Transduction and Targeted Therapy
Researchers discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient
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87 Activation and regulation of non-canonical NF-κB pathway Most of the non-canonical NF-κB receptors belong to the TNFR superfamily, including BAFF-R, CD40, LTβR, and receptor Activator of NF-KappaB (RANK), which are associated with the recruitment of different TRAF members and bind to the corresponding ligands as complexes
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