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Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis | Arthritis Research & Therapy | Springer Nature Link

These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages: primary prevention, concurrent treatment phase, postoperative recovery, maintenance therapy, and end‐of‐life care

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By contrast, immunologically “cold” tumors (characterized by low T-cell infiltration and limited inflammatory signaling) may be relatively less affected by ID through immune-mediated mechanisms, because their progression depends less on iron-sensitive immune surveillance (144, 145)