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However, in the case of SetCys, the reactivity of the selenol and thiol groups are intimately coupled as demonstrated by the reduced sensitivity of SetAla residue to carbon–nitrogen bond cleavage (Fig
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The Kelch-like ECH-associated protein 1 (Keap1)-Nrf2-activator protein-1 (AP-1)/antioxidant response element (ARE) signaling pathway increases the transcription of genes responsible for resistance to oxidative stress, including SLC7A11 [71,72]
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