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7 An alternative approach for production of chimeric human–animal antibodies is by using a humanized-rodent such as OmniRat that carries a chimeric human/rat IgH locus and a fully human Ig κ or Ig λ locus
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After 5 min, a portion of the n -BuLi mixture (1.9 ml, 1.5 mmol) was added dropwise to the aryl iodide solution, and the mixture was stirred at −78 °C for 30 min
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