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For proteomic analysis, the raw LC-MS datasets were first searched against database and converted into matrices containing normalized intensity (the raw intensity after correcting the sample/batch effect) of proteins
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Mechanistically, both fatty acid desaturases SCD and FADS2 are transcriptionally controlled by the sterol regulatory element binding protein 1 (SREBP1) downstream of the PI3K/AKT/rapamycin kinase complex 1 (mTORC1) signaling pathway [118]
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