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(Please see Sun Damage and Pigmentation category.) Also, “Superoxide radicals are produced by skin cells that are infected with Propionibacterium acnes, the bacterium that causes acne.” [9] B3-nicotinamide, a derivative of niacin, is required by the body for the production of certain coenzymes essential for proper functioning of superoxide dismutase
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On the basis of the results available up to date, the Global Initiative for Chronic Obstructive Lung Disease [119] recognizes that mucolytic and antioxidant drugs, such as NAC, can be used as an adjunct therapy to reduce the risk of acute exacerbation of COPD, but in a limited way due to the lack of robust randomized controlled clinical trials (level of evidence B)
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