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In the current study, to test whether having at least one of the two major cytosolic NADPH-dependent disulfide reductases is essential for hepatocyte survival in vivo , we ablated Txnrd1 , encoding TrxR1, in the hepatocytes of mice having a germline disruption of Gsr , encoding GR
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Nuclear Receptors Numerous cellular signaling pathways that affect cellular receptors, such as nuclear receptors, can be activated or inhibited by oxysterols
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