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as the founding director of Yale University's Prevention Research Center, past president of the American College of Lifestyle Medicine and founder of the non profit True Health Initiative, Dr
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However, GS deficiency in humans can result in generalized lower GSH levels and dramatic metabolic consequences because the accumulated γ-glutamylcysteine is converted to 5-oxoproline, which can cause severe metabolic acidosis, hemolytic anemia, and central nervous system damage (Shi et al., 1996)
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