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Also, FTH-deficient cardiomyocytes have reduced expression of the ferroptosis regulator SLC7A11, a subunit of the heterodimeric cystine-glutamate antiporter, that when overexpressed is associated with increased synthesis of GTH and inhibited lipid peroxidation, thus preventing ferroptosis [228,230]
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2011;32:2325.e7–2325.e16
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