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In turn, miR-214 targets and regulates the Unc-51-like autophagy activating kinase 1(ULK1), which hinders the initiation process of autophagy, leading to impaired autophagy in PTEC and thereby affecting the repair capacity of renal tissue ( In summary, p62 accumulates in DKD model podocytes and inhibits autophagic activity in renal podocytes
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