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PU.1, in cooperation with C/EBP, plays a critical role in opening chromatin at microglial enhancers (Yeh and Ikezu, 2019
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Mutations in the GluA2 gene, which have been identified in patients with intellectual disability, autism spectrum disorder, and epilepsy, have been found to cause defects in AMPAR-mediated synaptic transmission and voltage rectification 54
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