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Uncertainties and Inconsistencies There are a few uncertainties for consideration: The increase in reactive oxygen species could be the molecular initiating event - while this is true and an increase is ROS is a major contributor and key event to this AOP, proceeding is the event of oxidation of glutathione
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doi: 10.1084/jem.20221751, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Kitamoto S., Nagao-Kitamoto H., Jiao Y., Gillilland M
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