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Although there is a general consensus that endothelial dysfunction is a reliable indicator of the advancement of atherosclerosis and potential cardiovascular events, additional research is needed to fully understand its impact on hypertension and platelet hyperactivity
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The transport of long-chain fatty acyl-CoAs into the mitochondria is accomplished via an acyl-carnitine intermediate, which itself is generated by the action of carnitine palmitoyltransferase 1 (CPT1 or CPT-I), an enzyme that resides in the outer mitochondrial membrane
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