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Finally, MVs were sedimented from the concentrated supernatants through high-speed centrifugation at 150,000 g during 1.5 h at 4°C using an SW 41 rotor (Beckman Coulter) and an ultracentrifuge (Optima™ LE-80 K, Beckman Coulter)

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Although the results of these studies indicate that resveratrol has positive effects, it is worth noting that resveratrol was not supplemented alone, but always in combination with oral contraceptive pills